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Test-NO7.Rmd

Report NO7

Table of Contents

1 PK parameters

1.1 PK parameters for PO320mg

Table 1-1: PK parameters for PO320mg

Path Parameter Value Unit
Theophylline C_max 8.68 mg/l
Theophylline t_max 1.55 h
Theophylline C_tEnd 3.46 mg/l
Theophylline AUC_tEnd 151.57 mg*h/l



2 Time profiles and residual plots

2.1 Time profiles and residual plots for PO320mg

Figure 2-1: Time profiles for PO320mg. Data source: Boeckmann 1994. Time profiles are plotted in a linear scale.



Figure 2-2: Time profiles for PO320mg. Data source: Boeckmann 1994. Time profiles are plotted in a logarithmic scale.



Figure 2-3: Predicted vs observed for PO320mg. Data source: Boeckmann 1994. Predictions and observations are plotted in a linear scale.



Figure 2-4: Predicted vs observed for PO320mg. Data source: Boeckmann 1994. Predictions and observations are plotted in a logarithmic scale.



Figure 2-5: Logarithmic residuals vs predicted values for PO320mg. Data source: Boeckmann 1994.



Figure 2-6: Logarithmic residuals vs time values for PO320mg. Data source: Boeckmann 1994.



Figure 2-7: Logarithmic residuals distribution (stacked) for PO320mg. Data source: Boeckmann 1994.



Figure 2-8: Logarithmic residuals for PO320mg as quantile-quantile plot. Data source: Boeckmann 1994.