Raltegravir Mass Balance Report

Table of Contents

• 1 Mass Balance
  • 1.1 Mass Balance for Single Dose (100 mg)
    • 1.1.1 Mass Balance for Raltegravir
  • 1.2 Mass Balance for Multiple Doses (100 mg)
    • 1.2.1 Mass Balance for Raltegravir

1 Mass Balance

1.1 Mass Balance for Single Dose (100 mg)

1.1.1 Mass Balance for Raltegravir

Figure 1-1: Amount of drug vs time within the different compartments for Raltegravir

Figure 1-2: Cumulated amount of drug vs time within the different compartments for Raltegravir

Figure 1-3: Amount of drug vs time within the different compartments normalized to applicated drugmass for Raltegravir

Figure 1-4: Cumulated amount of drug vs time within the different compartments normalized to applicated drugmass for Raltegravir

Figure 1-5: Fraction of drug within the different compartments at 33.00h for Raltegravir

1.2 Mass Balance for Multiple Doses (100 mg)

1.2.1 Mass Balance for Raltegravir

Figure 1-6: Amount of drug vs time within the different compartments for Raltegravir

Figure 1-7: Cumulated amount of drug vs time within the different compartments for Raltegravir

Figure 1-8: Amount of drug vs time within the different compartments normalized to applicated drugmass for Raltegravir

Figure 1-9: Cumulated amount of drug vs time within the different compartments normalized to applicated drugmass for Raltegravir

Figure 1-10: Fraction of drug within the different compartments at 240.00h for Raltegravir